Article-Journal

Noninvasive, Multimodal Inflammatory Biomarker Discovery for Systemic Inflammation (NOVA Study): Protocol for a Cross-Sectional Study
Prolonged systemic inflammation is recognized as a major contributor to the development of various chronic inflammatory diseases. Daily …
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Noninvasive, Multimodal Inflammatory Biomarker Discovery for Systemic Inflammation (NOVA Study): Protocol for a Cross-Sectional Study
Circadian Rhythm Analysis Using Wearable-Based Accelerometry as a Digital Biomarker of Aging and Healthspan
Recognizing the pivotal role of circadian rhythm in the human aging process and its scalability through wearables, we introduce …
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Circadian Rhythm Analysis Using Wearable-Based Accelerometry as a Digital Biomarker of Aging and Healthspan
The Bitemporal Lens Model—toward a holistic approach to chronic disease prevention with digital biomarkers
We introduce the Bitemporal Lens Model, a comprehensive methodology for chronic disease prevention using digital biomarkers. The …
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The Bitemporal Lens Model—toward a holistic approach to chronic disease prevention with digital biomarkers
Wearable-based accelerometer activity profile as digital biomarker of inflammation, biological age, and mortality using hierarchical clustering analysis in NHANES 2011–2014
Repeated disruptions in circadian rhythms are associated with implications for health outcomes and longevity. The utilization of …
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Wearable-based accelerometer activity profile as digital biomarker of inflammation, biological age, and mortality using hierarchical clustering analysis in NHANES 2011–2014
Real-World First-Line Use of Pertuzumab With Different Taxanes for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: A Comparative Effectiveness Study Using US Electronic Health Records
On the basis of the results from CLEOPATRA, pertuzumab plus trastuzumab and chemotherapy is the first-line standard of care for human …
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Real-World First-Line Use of Pertuzumab With Different Taxanes for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: A Comparative Effectiveness Study Using US Electronic Health Records
Trastuzumab emtansine vs lapatinib and capecitabine in HER2-positive metastatic breast cancer brain metastases: A real-world study
Trastuzumab emtansine (T-DM1) has demonstrated improvements in survival and neurological symptoms in patients with breast cancer with …
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Trastuzumab emtansine vs lapatinib and capecitabine in HER2-positive metastatic breast cancer brain metastases: A real-world study
Association of baseline systemic corticosteroid use with overall survival and time to next treatment in patients receiving immune checkpoint inhibitor therapy in real-world US oncology practice for advanced non-small cell lung cancer, melanoma, or urothelial carcinoma
Immune checkpoint inhibitors (CPIs) have expanded treatment options for patients with solid tumors. Systemic corticosteroids (CSs) have …
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Association of baseline systemic corticosteroid use with overall survival and time to next treatment in patients receiving immune checkpoint inhibitor therapy in real-world US oncology practice for advanced non-small cell lung cancer, melanoma, or urothelial carcinoma
Association of systemic corticosteroids with overall survival in patients receiving cancer immunotherapy for advanced melanoma, non-small cell lung cancer or urothelial cancer in routine clinical practice
Corticosteroids (CS) are often prescribed for patients (pts) with cancer to alleviate disease symptoms, manage treatment-related …
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The Value of Novel Immuno-Oncology Treatments
Objectives-To assess the value to society of improved survival from novel immuno-oncology (I-O) treatments. Study Design-Case studies …
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The Value of Novel Immuno-Oncology Treatments
Measuring Sarcopenia Severity in Older Adults and the Value of Effective Interventions
Little is known about the severity and long-term health and economic consequences of sarcopenia. We developed a sarcopenia index to …
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Measuring Sarcopenia Severity in Older Adults and the Value of Effective Interventions